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The SNPs in pre-miRNA are related to the response of capecitabine-based therapy in advanced colon cancer patients

The single nucleotide polymorphisms (SNPs) in the microRNA precursor (pre-miRNA) may modulate the posttranscriptional regulation of gene expression and explain individual sensitivity to chemotherapy. Here we investigated the correlation between 23 SNPs in the pre-miRNA and the efficacy of capecitabi...

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Detalles Bibliográficos
Autores principales: Mao, Yong, Zou, Chengda, Meng, Fanyi, Kong, Jiehong, Wang, Weipeng, Hua, Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5805515/
https://www.ncbi.nlm.nih.gov/pubmed/29467929
http://dx.doi.org/10.18632/oncotarget.23190