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Characterization of aptamer-mediated gene delivery system for liver cancer therapy

Liver cancer is a fatal disease with limited therapy options. The recombinant adenovirus expressing tumor-suppressor gene of PTEN (Ad5-PTEN) showed effective antitumor activity against liver cancer. However, its disadvantages produced great limitation on its application, especially its nonspecific a...

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Detalles Bibliográficos
Autores principales: Liu, Zhongbing, Sun, Xiaoduan, Xiao, Shuangli, Lin, Yan, Li, Chunhong, Hao, Na, Zhou, Meiling, Deng, Ruolan, Ke, Siyun, Zhong, Zhirong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5805518/
https://www.ncbi.nlm.nih.gov/pubmed/29467932
http://dx.doi.org/10.18632/oncotarget.23564