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Identification and characterisation of NANOG+/ OCT-4(high)/SOX2+ doxorubicin-resistant stem-like cells from transformed trophoblastic cell lines

Treatment of gestational trophoblastic diseases (GTD) involves surgery, radiotherapy and chemotherapy. Although, these therapeutic approaches are highly successful, drug resistance and toxicity remain a concern for high risk patients. This Chemoresistance has also been observed in the presence of ca...

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Detalles Bibliográficos
Autores principales: Balahmar, Reham M., Boocock, David J., Coveney, Clare, Ray, Sankalita, Vadakekolathu, Jayakumar, Regad, Tarik, Ali, Selman, Sivasubramaniam, Shiva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5805535/
https://www.ncbi.nlm.nih.gov/pubmed/29467949
http://dx.doi.org/10.18632/oncotarget.24151