Multi-trait analysis of genome-wide association summary statistics using MTAG

We introduce Multi-Trait Analysis of GWAS (MTAG), a method for joint analysis of summary statistics from GWASs of different traits, possibly from overlapping samples. We apply MTAG to summary statistics for depressive symptoms (N(eff) = 354,862), neuroticism (N = 168,105), and subjective well-being...

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Detalles Bibliográficos
Autores principales: Turley, Patrick, Walters, Raymond K., Maghzian, Omeed, Okbay, Aysu, Lee, James J., Fontana, Mark Alan, Nguyen-Viet, Tuan Anh, Wedow, Robbee, Zacher, Meghan, Furlotte, Nicholas A., Magnusson, Patrik, Oskarsson, Sven, Johannesson, Magnus, Visscher, Peter M., Laibson, David, Cesarini, David, Neale, Benjamin M., Benjamin, Daniel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5805593/
https://www.ncbi.nlm.nih.gov/pubmed/29292387
http://dx.doi.org/10.1038/s41588-017-0009-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5805593/
https://www.ncbi.nlm.nih.gov/pubmed/29292387
http://dx.doi.org/10.1038/s41588-017-0009-4

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