Methylation profiling identifies two subclasses of squamous cell carcinoma related to distinct cells of origin

Cutaneous squamous cell carcinoma (cSCC) is the second most common skin cancer and usually progresses from a UV-induced precancerous lesion termed actinic keratosis (AK). Despite various efforts to characterize these lesions molecularly, the etiology of AK and its progression to cSCC remain partiall...

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Detalles Bibliográficos
Autores principales: Rodríguez-Paredes, Manuel, Bormann, Felix, Raddatz, Günter, Gutekunst, Julian, Lucena-Porcel, Carlota, Köhler, Florian, Wurzer, Elisabeth, Schmidt, Katrin, Gallinat, Stefan, Wenck, Horst, Röwert-Huber, Joachim, Denisova, Evgeniya, Feuerbach, Lars, Park, Jeongbin, Brors, Benedikt, Herpel, Esther, Nindl, Ingo, Hofmann, Thomas G., Winnefeld, Marc, Lyko, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5805678/
https://www.ncbi.nlm.nih.gov/pubmed/29422656
http://dx.doi.org/10.1038/s41467-018-03025-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5805678/
https://www.ncbi.nlm.nih.gov/pubmed/29422656
http://dx.doi.org/10.1038/s41467-018-03025-1

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