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LARP7-like protein Pof8 regulates telomerase assembly and poly(A)+TERRA expression in fission yeast
Telomerase is a reverse transcriptase complex that ensures stable maintenance of linear eukaryotic chromosome ends by overcoming the end replication problem, posed by the inability of replicative DNA polymerases to fully replicate linear DNA. The catalytic subunit TERT must be assembled properly wit...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5805695/ https://www.ncbi.nlm.nih.gov/pubmed/29422503 http://dx.doi.org/10.1038/s41467-018-02874-0 |