TGFβ1 reinforces arterial aging in the vascular smooth muscle cell through a long-range regulation of the cytoskeletal stiffness

Here we report exquisitely distinct material properties of primary vascular smooth muscle (VSM) cells isolated from the thoracic aorta of adult (8 months) vs. aged (30 months) F344XBN rats. Individual VSM cells derived from the aged animals showed a tense internal network of the actin cytoskeleton (...

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Detalles Bibliográficos
Autores principales: Zhu, Wanqu, Kim, Byoung Choul, Wang, Mingyi, Huang, Jessie, Isak, Abraham, Bexiga, Natalia M., Monticone, Robert, Ha, Taekjip, Lakatta, Edward G., An, Steven S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5805716/
https://www.ncbi.nlm.nih.gov/pubmed/29422510
http://dx.doi.org/10.1038/s41598-018-20763-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5805716/
https://www.ncbi.nlm.nih.gov/pubmed/29422510
http://dx.doi.org/10.1038/s41598-018-20763-w

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