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Skeletal myosin binding protein-C isoforms regulate thin filament activity in a Ca(2+)-dependent manner

Muscle contraction, which is initiated by Ca(2+), results in precise sliding of myosin-based thick and actin-based thin filament contractile proteins. The interactions between myosin and actin are finely tuned by three isoforms of myosin binding protein-C (MyBP-C): slow-skeletal, fast-skeletal, and...

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Detalles Bibliográficos
Autores principales: Lin, Brian Leei, Li, Amy, Mun, Ji Young, Previs, Michael J., Previs, Samantha Beck, Campbell, Stuart G., dos Remedios, Cristobal G., Tombe, Pieter de P., Craig, Roger, Warshaw, David M., Sadayappan, Sakthivel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5805719/
https://www.ncbi.nlm.nih.gov/pubmed/29422607
http://dx.doi.org/10.1038/s41598-018-21053-1