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Skeletal myosin binding protein-C isoforms regulate thin filament activity in a Ca(2+)-dependent manner
Muscle contraction, which is initiated by Ca(2+), results in precise sliding of myosin-based thick and actin-based thin filament contractile proteins. The interactions between myosin and actin are finely tuned by three isoforms of myosin binding protein-C (MyBP-C): slow-skeletal, fast-skeletal, and...
Autores principales: | Lin, Brian Leei, Li, Amy, Mun, Ji Young, Previs, Michael J., Previs, Samantha Beck, Campbell, Stuart G., dos Remedios, Cristobal G., Tombe, Pieter de P., Craig, Roger, Warshaw, David M., Sadayappan, Sakthivel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5805719/ https://www.ncbi.nlm.nih.gov/pubmed/29422607 http://dx.doi.org/10.1038/s41598-018-21053-1 |
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