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RAGE-aptamer attenuates deoxycorticosterone acetate/salt-induced renal injury in mice
The mineralocorticoid receptor (MR) and its downstream signaling play an important role in hypertensive renal injury. The interaction of advanced glycation end products (AGE) with their receptor (RAGE) is involved in the progression of renal disease. However, the pathological crosstalk between AGE–R...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5805738/ https://www.ncbi.nlm.nih.gov/pubmed/29422652 http://dx.doi.org/10.1038/s41598-018-21176-5 |