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Pof8 is a La-related protein and a constitutive component of telomerase in fission yeast

Telomerase reverse transcriptase (TERT) and the non-coding telomerase RNA subunit (TR) constitute the core of telomerase. Here we now report that the putative F-box protein Pof8 is also a constitutive component of active telomerase in fission yeast. Pof8 functions in a hierarchical assembly pathway...

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Detalles Bibliográficos
Autores principales: Páez-Moscoso, Diego J., Pan, Lili, Sigauke, Rutendo F., Schroeder, Morgan R., Tang, Wen, Baumann, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5805746/
https://www.ncbi.nlm.nih.gov/pubmed/29422664
http://dx.doi.org/10.1038/s41467-017-02284-8