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Notch signaling regulates Hey2 expression in a spatiotemporal dependent manner during cardiac morphogenesis and trabecular specification

Hey2 gene mutations in both humans and mice have been associated with multiple cardiac defects. However, the currently reported localization of Hey2 in the ventricular compact zone cannot explain the wide variety of cardiac defects. Furthermore, it was reported that, in contrast to other organs, Not...

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Detalles Bibliográficos
Autores principales: Miao, Lianjie, Li, Jingjing, Li, Jun, Tian, Xueying, Lu, Yangyang, Hu, Saiyang, Shieh, David, Kanai, Ryan, Zhou, Bo-yang, Zhou, Bin, Liu, Jiandong, Firulli, Anthony B., Martin, James F., Singer, Harold, Xin, Hongbo, Wu, Mingfu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5805758/
https://www.ncbi.nlm.nih.gov/pubmed/29422515
http://dx.doi.org/10.1038/s41598-018-20917-w