Small molecule anionophores promote transmembrane anion permeation matching CFTR activity

Anion selective ionophores, anionophores, are small molecules capable of facilitating the transmembrane transport of anions. Inspired in the structure of natural product prodigiosin, four novel anionophores 1a-d, including a 1,2,3-triazole group, were prepared. These compounds proved highly efficien...

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Detalles Bibliográficos
Autores principales: Hernando, Elsa, Capurro, Valeria, Cossu, Claudia, Fiore, Michele, García-Valverde, María, Soto-Cerrato, Vanessa, Pérez-Tomás, Ricardo, Moran, Oscar, Zegarra-Moran, Olga, Quesada, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5805763/
https://www.ncbi.nlm.nih.gov/pubmed/29422673
http://dx.doi.org/10.1038/s41598-018-20708-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5805763/
https://www.ncbi.nlm.nih.gov/pubmed/29422673
http://dx.doi.org/10.1038/s41598-018-20708-3

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