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Optimal compressed representation of high throughput sequence data via light assembly
The most effective genomic data compression methods either assemble reads into contigs, or replace them with their alignment positions on a reference genome. Such methods require significant computational resources, but faster alternatives that avoid using explicit or de novo-constructed references...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5805770/ https://www.ncbi.nlm.nih.gov/pubmed/29422526 http://dx.doi.org/10.1038/s41467-017-02480-6 |