LC–MS/MS-based quantitative study of the acyl group- and site-selectivity of human sirtuins to acylated nucleosomes

Chromatin structure and gene expression are dynamically regulated by posttranslational modifications of histones. Recent advance in mass spectrometry has identified novel types of lysine acylations, such as butyrylation and malonylation, whose functions and regulations are likely different from thos...

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Detalles Bibliográficos
Autores principales: Tanabe, Kana, Liu, Jiaan, Kato, Daiki, Kurumizaka, Hitoshi, Yamatsugu, Kenzo, Kanai, Motomu, Kawashima, Shigehiro A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5805777/
https://www.ncbi.nlm.nih.gov/pubmed/29422688
http://dx.doi.org/10.1038/s41598-018-21060-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5805777/
https://www.ncbi.nlm.nih.gov/pubmed/29422688
http://dx.doi.org/10.1038/s41598-018-21060-2

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