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Established Models and New Paradigms for Hypoxia-Driven Cancer-Associated Bone Disease
The five-year survival rate for primary bone cancers is ~ 70% while almost all cases of secondary metastatic bone cancer are terminal. Hypoxia, the deficiency of oxygen which occurs as the rate of tumour growth exceeds the supply of vascularisation, is a key promoter of tumour progression. Hypoxia-d...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer US
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5805797/ https://www.ncbi.nlm.nih.gov/pubmed/29098360 http://dx.doi.org/10.1007/s00223-017-0352-6 |