Gating mechanism of Kv11.1 (hERG) K(+) channels without covalent connection between voltage sensor and pore domains

Kv11.1 (hERG, KCNH2) is a voltage-gated potassium channel crucial in setting the cardiac rhythm and the electrical behaviour of several non-cardiac cell types. Voltage-dependent gating of Kv11.1 can be reconstructed from non-covalently linked voltage sensing and pore modules (split channels), challe...

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Detalles Bibliográficos
Autores principales: de la Peña, Pilar, Domínguez, Pedro, Barros, Francisco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Ion Channels, Receptors and Transporters
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5805800/
https://www.ncbi.nlm.nih.gov/pubmed/29270671
http://dx.doi.org/10.1007/s00424-017-2093-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5805800/
https://www.ncbi.nlm.nih.gov/pubmed/29270671
http://dx.doi.org/10.1007/s00424-017-2093-9

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