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The effect of aminoguanidine (AG) and pyridoxamine (PM) on ageing human cortical bone
OBJECTIVES: Advanced glycation end-products (AGEs) are a post-translational modification of collagen that form spontaneously in the skeletal matrix due to the presence of reducing sugars, such as glucose. The accumulation of AGEs leads to collagen cross-linking, which adversely affects bone quality...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5805823/ https://www.ncbi.nlm.nih.gov/pubmed/29363521 http://dx.doi.org/10.1302/2046-3758.71.BJR-2017-0135.R1 |