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The effect of aminoguanidine (AG) and pyridoxamine (PM) on ageing human cortical bone

OBJECTIVES: Advanced glycation end-products (AGEs) are a post-translational modification of collagen that form spontaneously in the skeletal matrix due to the presence of reducing sugars, such as glucose. The accumulation of AGEs leads to collagen cross-linking, which adversely affects bone quality...

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Detalles Bibliográficos
Autores principales:	Abar, O., Dharmar, S., Tang, S. Y.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2018
Materias:	Bone Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5805823/ https://www.ncbi.nlm.nih.gov/pubmed/29363521 http://dx.doi.org/10.1302/2046-3758.71.BJR-2017-0135.R1

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