Gut hormone polyagonists for the treatment of type 2 diabetes

Chemical derivatives of the gut-derived peptide hormone glucagon-like peptide 1 (GLP-1) are among the best-in-class pharmacotherapies to treat obesity and type 2 diabetes. However, GLP-1 analogs have modest weight lowering capacity, in the range of 5–10%, and the therapeutic window is hampered by do...

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Detalles Bibliográficos
Autores principales: Brandt, Sara J., Götz, Anna, Tschöp, Matthias H., Müller, Timo D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science Inc 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5805859/
https://www.ncbi.nlm.nih.gov/pubmed/29412819
http://dx.doi.org/10.1016/j.peptides.2017.12.021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5805859/
https://www.ncbi.nlm.nih.gov/pubmed/29412819
http://dx.doi.org/10.1016/j.peptides.2017.12.021

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