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Efficient analysis of stochastic gene dynamics in the non-adiabatic regime using piecewise deterministic Markov processes
Single-cell experiments show that gene expression is stochastic and bursty, a feature that can emerge from slow switching between promoter states with different activities. In addition to slow chromatin and/or DNA looping dynamics, one source of long-lived promoter states is the slow binding and unb...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5805981/ https://www.ncbi.nlm.nih.gov/pubmed/29386401 http://dx.doi.org/10.1098/rsif.2017.0804 |