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Improving the Transduction of Bone Marrow–Derived Cells with an Integrase-Defective Lentiviral Vector

In lentiviral vector (LV) applications where transient transgene expression is sufficient, integrase-defective lentiviral vectors (IDLVs) are beneficial for reducing the potential for off-target effects associated with insertional mutagenesis. It was previously demonstrated that human RPE65 mRNA exp...

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Detalles Bibliográficos
Autores principales: Pay, S. Louise, Qi, Xiaoping, Willard, Jeffrey F., Godoy, Juliana, Sankhavaram, Kavya, Horton, Ranier, Mitter, Sayak K., Quigley, Judith L., Chang, Lung-Ji, Grant, Maria B., Boulton, Michael E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5806075/
https://www.ncbi.nlm.nih.gov/pubmed/29160102
http://dx.doi.org/10.1089/hgtb.2017.082