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Inhibition of the Vapor-Mediated Phase Transition of the High Temperature Form of Pyrazinamide

[Image: see text] Tailor-made additives can prove an effective method to prolong the lifetime of metastable forms of pharmaceutical compounds by surface stabilization. Pyrazinamide (PZA) is a pharmaceutical compound with four polymorphic forms. The high temperature γ form, which can be produced by s...

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Detalles Bibliográficos
Autores principales: Smets, M. M. H., Baaklini, G., Tijink, A., Sweers, L., Vossen, C. H. F., Brandel, C., Meekes, H., Cuppen, H. M., Coquerel, G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5806087/
https://www.ncbi.nlm.nih.gov/pubmed/29445318
http://dx.doi.org/10.1021/acs.cgd.7b01550