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SALL4 ‐ KHDRBS3 network enhances stemness by modulating CD44 splicing in basal‐like breast cancer

Understanding the mechanism by which cancer cells enhance stemness facilitates cancer therapies. Here, we revealed that a stem cell transcription factor, SALL4, functions to enhance stemness in basal‐like breast cancer cells. We used shRNA‐mediated knockdown and gene overexpression systems to analyz...

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Detalles Bibliográficos
Autores principales: Matsumoto, Yoshiaki, Itou, Junji, Sato, Fumiaki, Toi, Masakazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5806117/
https://www.ncbi.nlm.nih.gov/pubmed/29356399
http://dx.doi.org/10.1002/cam4.1296