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CBX7 regulates stem cell-like properties of gastric cancer cells via p16 and AKT-NF-κB-miR-21 pathways

BACKGROUND: Chromobox protein homolog 7 (CBX7), a member of the polycomb group (PcG) family of proteins, is involved in the regulation of cell proliferation and cancer progression. PcG family members, such as BMI, Mel-18, and EZH2, are integral constituents of the polycomb repressive complexes (PRCs...

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Detalles Bibliográficos
Autores principales: Ni, Su-Jie, Zhao, Li-Qin, Wang, Xiao-Feng, Wu, Zhen-Hua, Hua, Rui-Xi, Wan, Chun-Hua, Zhang, Jie-Yun, Zhang, Xiao-Wei, Huang, Ming-Zhu, Gan, Lu, Sun, Hua-Lin, Dimri, Goberdhan P., Guo, Wei-Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5806263/
https://www.ncbi.nlm.nih.gov/pubmed/29422082
http://dx.doi.org/10.1186/s13045-018-0562-z