Adiponectin aggravates bone erosion by promoting osteopontin production in synovial tissue of rheumatoid arthritis

BACKGROUND: We have previously reported that adiponectin (AD), an adipokine that is secreted by adipocytes, correlates well with progressive bone erosion in rheumatoid arthritis (RA). The exact mechanism of AD in promoting joint destruction remains unclear. Osteopontin (OPN) is required for osteocla...

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Detalles Bibliográficos
Autores principales: Qian, Jie, Xu, Lingxiao, Sun, Xiaoxuan, Wang, Yani, Xuan, Wenhua, Zhang, Qian, Zhao, Pengfei, Wu, Qin, Liu, Rui, Che, Nan, Wang, Fang, Tan, Wenfeng, Zhang, Miaojia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5806355/
https://www.ncbi.nlm.nih.gov/pubmed/29422077
http://dx.doi.org/10.1186/s13075-018-1526-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5806355/
https://www.ncbi.nlm.nih.gov/pubmed/29422077
http://dx.doi.org/10.1186/s13075-018-1526-y

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