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Effects of Ovariectomy in an hSOD1-G93A Transgenic Mouse Model of Amyotrophic Lateral Sclerosis (ALS)

BACKGROUND: Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disorder characterized by progressive muscular dystrophy and paralysis; most ALS patients die from respiratory failure within 3 to 5 years, and there is currently no effective treatment. Some studies have indicated se...

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Detalles Bibliográficos
Autores principales: Yan, Lina, Liu, Yaling, Sun, Can, Zheng, Qian, Hao, Pengli, Zhai, Jingxu, Liu, Yuanyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5806477/
https://www.ncbi.nlm.nih.gov/pubmed/29394243
http://dx.doi.org/10.12659/MSM.908786