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Assessing the performance of a Loop Mediated Isothermal Amplification (LAMP) assay for the detection and subtyping of high-risk suptypes of Human Papilloma Virus (HPV) for Oropharyngeal Squamous Cell Carcinoma (OPSCC) without DNA purification

BACKGROUND: Oropharyngeal Squamous Cell Carcinoma (OPSCC) is increasing in incidence despite a decline in traditional risk factors. Human Papilloma Virus (HPV), specifically subtypes 16, 18, 31 and 35, has been implicated as the high-risk etiologic agent. HPV positive cancers have a significantly be...

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Detalles Bibliográficos
Autores principales: Rohatensky, Mitchell G., Livingstone, Devon M., Mintchev, Paul, Barnes, Heather K., Nakoneshny, Steven C., Demetrick, Douglas J., Dort, Joseph C., van Marle, Guido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5806493/
https://www.ncbi.nlm.nih.gov/pubmed/29422018
http://dx.doi.org/10.1186/s12885-018-4087-1