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Alphavirus vector-based replicon particles expressing multivalent cross-protective Lassa virus glycoproteins
Lassa virus (LASV) is the most prevalent rodent-borne arenavirus circulated in West Africa. With population at risk from Senegal to Nigeria, LASV causes Lassa fever and is responsible for thousands of deaths annually. High genetic diversity of LASV is one of the challenges for vaccine R&D. We de...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5806529/ https://www.ncbi.nlm.nih.gov/pubmed/29287681 http://dx.doi.org/10.1016/j.vaccine.2017.12.046 |