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Alphavirus vector-based replicon particles expressing multivalent cross-protective Lassa virus glycoproteins

Lassa virus (LASV) is the most prevalent rodent-borne arenavirus circulated in West Africa. With population at risk from Senegal to Nigeria, LASV causes Lassa fever and is responsible for thousands of deaths annually. High genetic diversity of LASV is one of the challenges for vaccine R&D. We de...

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Detalles Bibliográficos
Autores principales: Wang, Min, Jokinen, Jenny, Tretyakova, Irina, Pushko, Peter, Lukashevich, Igor S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5806529/
https://www.ncbi.nlm.nih.gov/pubmed/29287681
http://dx.doi.org/10.1016/j.vaccine.2017.12.046