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Temporal Changes in the Cerebrospinal Fluid Level of Hypocretin-1 and Histamine in Narcolepsy

STUDY OBJECTIVES: To follow the temporal changes of cerebrospinal fluid (CSF) biomarker levels in narcoleptic patients with unexpected hypocretin level at referral. METHODS: From 2007 to 2015, 170 human leukocyte antigen (HLA) DQB1*06:02-positive patients with primary narcolepsy and definite (n = 15...

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Detalles Bibliográficos
Autores principales: Lopez, Régis, Barateau, Lucie, Evangelista, Elisa, Chenini, Sofiene, Robert, Philippe, Jaussent, Isabelle, Dauvilliers, Yves
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5806580/
https://www.ncbi.nlm.nih.gov/pubmed/28364477
http://dx.doi.org/10.1093/sleep/zsw010