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Transient Receptor Potential Channels TRPM4 and TRPC3 Critically Contribute to Respiratory Motor Pattern Formation but not Rhythmogenesis in Rodent Brainstem Circuits

Transient receptor potential channel, TRPM4, the putative molecular substrate for Ca(2+)-activated nonselective cation current (I(CAN)), is hypothesized to generate bursting activity of pre-Bötzinger complex (pre-BötC) inspiratory neurons and critically contribute to respiratory rhythmogenesis. Anot...

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Detalles Bibliográficos
Autores principales: Koizumi, Hidehiko, John, Tibin T., Chia, Justine X., Tariq, Mohammad F., Phillips, Ryan S., Mosher, Bryan, Chen, Yonghua, Thompson, Ryan, Zhang, Ruli, Koshiya, Naohiro, Smith, Jeffrey C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5806591/
https://www.ncbi.nlm.nih.gov/pubmed/29435486
http://dx.doi.org/10.1523/ENEURO.0332-17.2018