Cargando…

Asymmetric PI3K Activity in Lymphocytes Organized by a PI3K-Mediated Polarity Pathway

Unequal transmission of nutritive signaling during cell division establishes fate disparity between sibling lymphocytes, but how asymmetric signaling becomes organized is not understood. We show that receptor-associated class I phosphatidylinositol 3-kinase (PI3K) signaling activity, indexed by phos...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Yen-Hua, Kratchmarov, Radomir, Lin, Wen-Hsuan W., Rothman, Nyanza J., Yen, Bonnie, Adams, William C., Nish, Simone A., Rathmell, Jeffrey C., Reiner, Steven L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5806629/
https://www.ncbi.nlm.nih.gov/pubmed/29420173
http://dx.doi.org/10.1016/j.celrep.2017.12.087