Cargando…

Asymmetric PI3K Activity in Lymphocytes Organized by a PI3K-Mediated Polarity Pathway

Unequal transmission of nutritive signaling during cell division establishes fate disparity between sibling lymphocytes, but how asymmetric signaling becomes organized is not understood. We show that receptor-associated class I phosphatidylinositol 3-kinase (PI3K) signaling activity, indexed by phos...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Yen-Hua, Kratchmarov, Radomir, Lin, Wen-Hsuan W., Rothman, Nyanza J., Yen, Bonnie, Adams, William C., Nish, Simone A., Rathmell, Jeffrey C., Reiner, Steven L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5806629/ https://www.ncbi.nlm.nih.gov/pubmed/29420173 http://dx.doi.org/10.1016/j.celrep.2017.12.087

Ejemplares similares

CD4(+) T cell effector commitment coupled to self-renewal by asymmetric cell divisions
por: Nish, Simone A., et al.
Publicado: (2017)

IRF4 Couples Anabolic Metabolism to Th1 Cell Fate Determination
por: Kratchmarov, Radomir, et al.
Publicado: (2017)

Determination of the branching ratios $\Gamma(K_{L} \to 3\pi^{0}) / \Gamma(K_{L} \to \pi^{+}\pi^{-}\pi^{0})$ and $\Gamma(K_{L} \to 3\pi^{0}) / \Gamma(K_{L} \to \pi e\nu)$
por: Kreutz, A., et al.
Publicado: (1994)

Selection Study for B+- -> (K-+ pi+- pi-+ pi+-)D K+- and B+- -> (K+ K- pi+ pi-)D K+-".
por: Hunt, P, et al.
Publicado: (2009)

Control of T lymphocyte fate decisions by PI3K signaling
por: Murter, Benjamin, et al.
Publicado: (2020)

$\pi \pi$ scattering lengths and $K \to 3\pi$ decays
por: Gallorini, Stefano
Publicado: (2013)

Regulation of T cell alloimmunity by PI3Kγ and PI3Kδ
por: Uehara, Mayuko, et al.
Publicado: (2017)

The investigation of $K^+\pi^−, \pi^+K^−$ and $\pi^+\pi^−$ atoms
por: Yazkov, Valeriy
Publicado: (2016)

Clonal Bifurcation of Foxp3 Expression Visualized in Thymocytes and T Cells
por: Yen, Bonnie, et al.
Publicado: (2018)

Study of the K+K-pi+pi- system centrally produced in the reactions pi+p --> pi+(K+K-pi+pi-)p and pp --> p(K+K-pi+pi-)p at 85 GeV/c
por: Armstrong, T A, et al.
Publicado: (1986)

Measurement of the absolute branching fractions for D$^{0}$ decays into K$^{-}\pi^{+}$, K$^{-}\pi^{+}\pi^{+}\pi^{-}$, $\overline{K}^{0}\pi^{+}\pi^{-}$
por: Albrecht, H, et al.
Publicado: (1994)

Observation of $\pi^- K^+$ and $\pi^+ K^-$ atoms
por: Adeva, B., et al.
Publicado: (2016)

Study of the $\overline{K} \pi \pi$ system produced in $K^{-}$ p -> $\overline{K} \pi \pi$ N reactions at 14.3 GeV/c
por: Barloutaud, R, et al.
Publicado: (1973)

Protoniumvernichtung in $K_{L}^{0} K^{\pm} \pi^{\mp} \pi^{0}$ und $K_{L}^{0} K^{\pm} \pi^{\mp} \pi^{0} \pi^{0}$
por: Kolo, C
Publicado: (1995)

Measurement of $Br(K_{S} \to \pi^{+}\pi^{-}\pi^{0})$ and limit on the CP violating decay $Br(K_{S} \to 3\pi^{0})$
por: Wache, Martin
Publicado: (2005)

Proposal: The measurement of polarization in backward scattering for the reactions $\pi^{+}p \rightarrow p\pi^{+} , K^{+} p \rightarrow pK^{+}$ and $\pi^{+}p \rightarrow \Sigma^{+}K^{+}$
por: Bradamante, Franco, et al.
Publicado: (1970)

Observation of $\pi^- K^+$ and $\pi^+ K^-$ atoms
por: Yazkov, Valeriy
Publicado: (2018)

$pp^{-}$ annihilation into $K^{+}K^{-}$ and $\pi^{+}\pi^{-}$
por: Witzig, Christoph
Publicado: (1991)

Study of $\tau$ decays to $K K \pi$ and $K \pi \pi$ at LEP, with DELPHI
por: Cavallo, F R
Publicado: (1997)

A measurement of the ratios of the rates $K^{0}_{L}$ -> 3 $\pi^{0}$ / $K^{0}_{L}$ -> $\pi^{+} \pi^{-} \pi^{0}$ , $K^{0}_{L}$ -> 3 $\pi^{0}$ / $K^{0}_{L}$ -> all charged modes and $K^{0}_{L}$ -> $\pi \mu \nu$ / $K^{0}_{L}$ -> $\pi$ e $\mu$ , and test of the $\delta$ I = 1/2 rule
por: Budagov, I A, et al.
Publicado: (1968)

A measure of the ratio of the rates $\frac{K_{L}\rightarrow 3 \pi^{0}}{K_{L}\rightarrow \pi^{+}\pi^{-}\pi^{0}}$ and $\frac{K_{L}\rightarrow 3 \pi^{0}}{K_{L}\rightarrow all charged}$
Publicado: (1967)

Measurement of relative branching fractions for D$^{+}$ --> K$^{-}$K$^{+}$K$^{+}$ and D$_{s}^{+}$ --> $\pi^{-}\pi^{+ }\pi^{+}$ decays
por: Adamovich, M I, et al.
Publicado: (1993)

PI3K Pathway in NSCLC
por: Martinez-Martí, Alex, et al.
Publicado: (2012)

$K_{A} \rightarrow K^{*} \pi and K^{*} \rightarrow K \pi$ decays
por: Srivastava, P P
Publicado: (1967)

The kaon B-parameter and K$^{-}\pi$ and K$^{-}\pi\pi$ transition amplitudes on the lattice
por: Gavela-Legazpi, Maria Belen, et al.
Publicado: (1988)

Biological characterization of SN32976, a selective inhibitor of PI3K and mTOR with preferential activity to PI3Kα, in comparison to established pan PI3K inhibitors
por: Rewcastle, Gordon W, et al.
Publicado: (2017)

Coherent production of $K^{+} \pi^{+} \pi^{-}$ on nuclei and determination of the $K^{+} \pi^{+} \pi^{-}$ - nucleon cross section
por: Bemporad, C, et al.
Publicado: (1973)

PI3Kδ Is Essential for Tumor Clearance Mediated by Cytotoxic T Lymphocytes
por: Putz, Eva Maria, et al.
Publicado: (2012)

Roles of PI3Kγ and PI3Kδ in mantle cell lymphoma proliferation and migration contributing to efficacy of the PI3Kγ/δ inhibitor duvelisib
por: Till, Kathleen J., et al.
Publicado: (2023)

The reaction p + p --> K + K + pi + pi
por: Steinberger, Jack
Publicado: (1966)

Experimental investigation of $\pi^+\pi^-$ and $K^+K^-$ atoms
por: Afanasyev, Leonid
Publicado: (2019)

Study of the tracking efficiency for $D^0$ decays into $K\pi \pi \pi$ and $K\pi$
por: Goncalves Abrantes, Fernanda
Publicado: (2017)

Measurement of the reactions $\pi^{-} + p\to \pi^{+} + \pi^{-} + n, \pi^{-} + p \to K^{+} + K^{-}+ n$
por: Dietl, H, et al.
Publicado: (1968)

Polarization in $\pi^{-}p \to K^{+}\Sigma^{-}$ backward scattering at 3.5 GeV/c
por: Bradamante, Franco, et al.
Publicado: (Jun )

Search for the suppressed decays $B^{+}\rightarrow K^{+}K^{+}\pi^{-}$ and $B^{+}\rightarrow \pi^{+}\pi^{+}K^{-}$
por: Aaij, Roel, et al.
Publicado: (2016)

First determination of the CP content of $D \to \pi^+ \pi^- \pi^0$ and $D \to K^+K^-\pi^0$
por: Nayak, M., et al.
Publicado: (2014)

On the phase of $\eta _{\pm } =A(K_{L}\rightarrow \pi ^{+}\pi ^{-})/A(K_{S}\rightarrow \pi ^{+}\pi ^{-})$
por: Darriulat, Pierre, et al.
Publicado: (1969)

The phase difference between $K _{L} \rightarrow \pi ^{+}\pi ^{-} $ and $K_{S} \rightarrow \pi^{+}\pi ^{-}$ decay amplitudes
por: Böhm, A, et al.
Publicado: (1969)

Model-independent search for $CP$ violation in $D^{0} \to K^{-}K^{+}\pi^{-}\pi^{+}$ and $D^{0} \to \pi^{-}\pi^{+}\pi^{+}\pi^{-}$ decays
por: Aaij, R, et al.
Publicado: (2013)

Search for rare B decays: B --> pi+ pi-, B --> K+ pi- and B --> K+ K-
por: Boucrot, J, et al.
Publicado: (1993)

Cannot write session to /tmp/vufind_sessions/sess_olv7976t6t09its2iqh4nppinj