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Estimating kinetic mechanisms with prior knowledge I: Linear parameter constraints
To understand how ion channels and other proteins function at the molecular and cellular levels, one must decrypt their kinetic mechanisms. Sophisticated algorithms have been developed that can be used to extract kinetic parameters from a variety of experimental data types. However, formulating mode...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5806684/ https://www.ncbi.nlm.nih.gov/pubmed/29321264 http://dx.doi.org/10.1085/jgp.201711911 |