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Estimating kinetic mechanisms with prior knowledge I: Linear parameter constraints

To understand how ion channels and other proteins function at the molecular and cellular levels, one must decrypt their kinetic mechanisms. Sophisticated algorithms have been developed that can be used to extract kinetic parameters from a variety of experimental data types. However, formulating mode...

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Detalles Bibliográficos
Autores principales: Salari, Autoosa, Navarro, Marco A., Milescu, Mirela, Milescu, Lorin S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5806684/
https://www.ncbi.nlm.nih.gov/pubmed/29321264
http://dx.doi.org/10.1085/jgp.201711911