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Downregulation of L-arginine metabolism in dendritic cells induces tolerance to exogenous antigen

Dendritic cells (DC) are potential tools for therapeutic applications and several strategies to generate tolerogenic DCs are under investigation. When activated by cytokines and microbial products, DCs express mediators that modulate immune responses. In this regard, the metabolites generated by the...

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Detalles Bibliográficos
Autores principales: Simioni, Patricia U, Fernandes, Luis GR, Tamashiro, Wirla MSC
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5806782/
https://www.ncbi.nlm.nih.gov/pubmed/27903843
http://dx.doi.org/10.1177/0394632016678873