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Immunological effects of everolimus in patients with metastatic renal cell cancer

The mammalian target of rapamycin (mTOR) is a crucial kinase present in all cells. Besides its role in the regulation of cell-growth, proliferation, angiogenesis, and survival of malignant tumors, mTOR additionally plays an important role in immune regulation by controlling the balance between effec...

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Detalles Bibliográficos
Autores principales: Huijts, Charlotte M, Santegoets, Saskia J, de Jong, Tamarah D, Verheul, Henk M, de Gruijl, Tanja D, van der Vliet, Hans J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5806813/
https://www.ncbi.nlm.nih.gov/pubmed/28988508
http://dx.doi.org/10.1177/0394632017734459