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Retinal genes are differentially expressed in areas of primary versus secondary degeneration following partial optic nerve injury

BACKGROUND: Partial transection (PT) of the optic nerve is an established experimental model of secondary degeneration in the central nervous system. After a dorsal transection, retinal ganglion cells (RGCs) with axons in ventral optic nerve are intact but vulnerable to secondary degeneration, where...

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Detalles Bibliográficos
Autores principales: Chiha, Wissam, LeVaillant, Chrisna J., Bartlett, Carole A., Hewitt, Alex W., Melton, Phillip E., Fitzgerald, Melinda, Harvey, Alan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5806857/
https://www.ncbi.nlm.nih.gov/pubmed/29425209
http://dx.doi.org/10.1371/journal.pone.0192348