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Friend virus limits adaptive cellular immune responses by imprinting a maturation-resistant and T helper type 2-biased immunophenotype in dendritic cells

The murine Friend virus (FV) retrovirus model has been widely used to study anti-viral immune responses, and virus-induced cancer. Here we analyzed FV immune evasion mechanisms on the level of dendritic cells (DC) essential for the induction of primary adaptive immune responses. Comparative quantita...

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Detalles Bibliográficos
Autores principales: Shen, Limei, Tenzer, Stefan, Hess, Moritz, Distler, Ute, Tubbe, Ingrid, Montermann, Evelyn, Schimmer, Simone, Dittmer, Ulf, Grabbe, Stephan, Bros, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5806892/
https://www.ncbi.nlm.nih.gov/pubmed/29425215
http://dx.doi.org/10.1371/journal.pone.0192541