Novel genetic polymorphisms associated with severe malaria and under selective pressure in North-eastern Tanzania

Significant selection pressure has been exerted on the genomes of human populations exposed to Plasmodium falciparum infection, resulting in the acquisition of mechanisms of resistance against severe malarial disease. Many host genetic factors, including sickle cell trait, have been associated with...

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Detalles Bibliográficos
Autores principales: Ravenhall, Matt, Campino, Susana, Sepúlveda, Nuno, Manjurano, Alphaxard, Nadjm, Behzad, Mtove, George, Wangai, Hannah, Maxwell, Caroline, Olomi, Raimos, Reyburn, Hugh, Drakeley, Christopher J., Riley, Eleanor M., Clark, Taane G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5806895/
https://www.ncbi.nlm.nih.gov/pubmed/29381699
http://dx.doi.org/10.1371/journal.pgen.1007172

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5806895/
https://www.ncbi.nlm.nih.gov/pubmed/29381699
http://dx.doi.org/10.1371/journal.pgen.1007172

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