Role of the AP-5 adaptor protein complex in late endosome-to-Golgi retrieval

The AP-5 adaptor protein complex is presumed to function in membrane traffic, but so far nothing is known about its pathway or its cargo. We have used CRISPR-Cas9 to knock out the AP-5 ζ subunit gene, AP5Z1, in HeLa cells, and then analysed the phenotype by subcellular fractionation profiling and qu...

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Detalles Bibliográficos
Autores principales: Hirst, Jennifer, Itzhak, Daniel N., Antrobus, Robin, Borner, Georg H. H., Robinson, Margaret S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5806898/
https://www.ncbi.nlm.nih.gov/pubmed/29381698
http://dx.doi.org/10.1371/journal.pbio.2004411

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5806898/
https://www.ncbi.nlm.nih.gov/pubmed/29381698
http://dx.doi.org/10.1371/journal.pbio.2004411

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