Sodium channel current loss of function in induced pluripotent stem cell-derived cardiomyocytes from a Brugada syndrome patient

Brugada syndrome predisposes to sudden death due to disruption of normal cardiac ion channel function, yet our understanding of the underlying cellular mechanisms is incomplete. Commonly used heterologous expression models lack many characteristics of native cardiomyocytes and, in particular, the in...

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Detalles Bibliográficos
Autores principales: Selga, Elisabet, Sendfeld, Franziska, Martinez-Moreno, Rebecca, Medine, Claire N., Tura-Ceide, Olga, Wilmut, Sir Ian, Pérez, Guillermo J., Scornik, Fabiana S., Brugada, Ramon, Mills, Nicholas L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5807028/
https://www.ncbi.nlm.nih.gov/pubmed/29024690
http://dx.doi.org/10.1016/j.yjmcc.2017.10.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5807028/
https://www.ncbi.nlm.nih.gov/pubmed/29024690
http://dx.doi.org/10.1016/j.yjmcc.2017.10.002

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