BI2536, a potent and selective inhibitor of polo-like kinase 1, in combination with cisplatin exerts synergistic effects on gastric cancer cells

BI2536 is a highly selective and potent inhibitor of polo-like kinase 1 (PLK1). In this study, we aimed to determine whether BI2536 and cisplatin can synergistically inhibit the malignant behavior of gastric cancer cells. For this purpose, the expression of PLK1 in gastric cancer cells was determine...

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Detalles Bibliográficos
Autores principales: Lian, Guodong, Li, Leping, Shi, Yulong, Jing, Changqing, Liu, Jinglei, Guo, Xiaobo, Zhang, Qingqing, Dai, Tianyu, Ye, Fei, Wang, Yanyan, Chen, Man
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5807034/
https://www.ncbi.nlm.nih.gov/pubmed/29393385
http://dx.doi.org/10.3892/ijo.2018.4255

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5807034/
https://www.ncbi.nlm.nih.gov/pubmed/29393385
http://dx.doi.org/10.3892/ijo.2018.4255

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