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BI2536, a potent and selective inhibitor of polo-like kinase 1, in combination with cisplatin exerts synergistic effects on gastric cancer cells
BI2536 is a highly selective and potent inhibitor of polo-like kinase 1 (PLK1). In this study, we aimed to determine whether BI2536 and cisplatin can synergistically inhibit the malignant behavior of gastric cancer cells. For this purpose, the expression of PLK1 in gastric cancer cells was determine...
Autores principales: | Lian, Guodong, Li, Leping, Shi, Yulong, Jing, Changqing, Liu, Jinglei, Guo, Xiaobo, Zhang, Qingqing, Dai, Tianyu, Ye, Fei, Wang, Yanyan, Chen, Man |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5807034/ https://www.ncbi.nlm.nih.gov/pubmed/29393385 http://dx.doi.org/10.3892/ijo.2018.4255 |
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