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Nuclear GSK3β induces DNA double-strand break repair by phosphorylating 53BP1 in glioblastoma
Glioblastoma is the most malignant and lethal subtype brain tumors with high risk of recurrence and therapeutic resistance. Emerging evidence has indicated that glycogen synthesis kinase 3 (GSK3)β plays oncogenic roles in multiple tumor types; however, the underlying mechanisms remain largely unknow...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5807039/ https://www.ncbi.nlm.nih.gov/pubmed/29328365 http://dx.doi.org/10.3892/ijo.2018.4237 |