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Nuclear GSK3β induces DNA double-strand break repair by phosphorylating 53BP1 in glioblastoma

Glioblastoma is the most malignant and lethal subtype brain tumors with high risk of recurrence and therapeutic resistance. Emerging evidence has indicated that glycogen synthesis kinase 3 (GSK3)β plays oncogenic roles in multiple tumor types; however, the underlying mechanisms remain largely unknow...

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Detalles Bibliográficos
Autores principales: Yang, Yong, Lei, Tiantian, Du, Suya, Tong, Rongsheng, Wang, Hailian, Yang, Jiao, Huang, Juan, Sun, Minghan, Wang, Yi, Dong, Zhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5807039/
https://www.ncbi.nlm.nih.gov/pubmed/29328365
http://dx.doi.org/10.3892/ijo.2018.4237