Eradication of cervical cancer in vivo by an AAV vector that encodes shRNA targeting human papillomavirus type 16 E6/E7

The major causative agent of cervical cancer is human papilloma virus (HPV); the viral proteins E6 and E7 induce carcinogenesis through the inactivation of the host tumor-suppressor gene. Therefore, the stable expression of specific inhibitors of E6 and E7 in cancer cells is expected to provide effe...

Descripción completa

Detalles Bibliográficos
Autores principales: Sato, Naoto, Saga, Yasushi, Uchibori, Ryosuke, Tsukahara, Tomonori, Urabe, Masashi, Kume, Akihiro, Fujiwara, Hiroyuki, Suzuki, Mitsuaki, Ozawa, Keiya, Mizukami, Hiroaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5807046/
https://www.ncbi.nlm.nih.gov/pubmed/29344635
http://dx.doi.org/10.3892/ijo.2018.4245

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5807046/
https://www.ncbi.nlm.nih.gov/pubmed/29344635
http://dx.doi.org/10.3892/ijo.2018.4245

Ejemplares similares