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Differential requirements of androgen receptor in luminal progenitors during prostate regeneration and tumor initiation

Master regulatory genes of tissue specification play key roles in stem/progenitor cells and are often important in cancer. In the prostate, androgen receptor (AR) is a master regulator essential for development and tumorigenesis, but its specific functions in prostate stem/progenitor cells have not...

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Detalles Bibliográficos
Autores principales: Chua, Chee Wai, Epsi, Nusrat J, Leung, Eva Y, Xuan, Shouhong, Lei, Ming, Li, Bo I, Bergren, Sarah K, Hibshoosh, Hanina, Mitrofanova, Antonina, Shen, Michael M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5807048/
https://www.ncbi.nlm.nih.gov/pubmed/29334357
http://dx.doi.org/10.7554/eLife.28768