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Unique molecular events during reprogramming of human somatic cells to induced pluripotent stem cells (iPSCs) at naïve state

Derivation of human naïve cells in the ground state of pluripotency provides promising avenues for developmental biology studies and therapeutic manipulations. However, the molecular mechanisms involved in the establishment and maintenance of human naïve pluripotency remain poorly understood. Using...

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Detalles Bibliográficos
Autores principales: Wang, Yixuan, Zhao, Chengchen, Hou, Zhenzhen, Yang, Yuanyuan, Bi, Yan, Wang, Hong, Zhang, Yong, Gao, Shaorong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5807049/
https://www.ncbi.nlm.nih.gov/pubmed/29381138
http://dx.doi.org/10.7554/eLife.29518