Robo1 Forms a Compact Dimer-of-Dimers Assembly

Roundabout (Robo) receptors provide an essential repulsive cue in neuronal development following Slit ligand binding. This important signaling pathway can also be hijacked in numerous cancers, making Slit-Robo an attractive therapeutic target. However, little is known about how Slit binding mediates...

Descripción completa

Detalles Bibliográficos
Autores principales: Aleksandrova, Nataliia, Gutsche, Irina, Kandiah, Eaazhisai, Avilov, Sergiy V., Petoukhov, Maxim V., Seiradake, Elena, McCarthy, Andrew A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5807052/
https://www.ncbi.nlm.nih.gov/pubmed/29307485
http://dx.doi.org/10.1016/j.str.2017.12.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5807052/
https://www.ncbi.nlm.nih.gov/pubmed/29307485
http://dx.doi.org/10.1016/j.str.2017.12.003

Ejemplares similares