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Saposin Lipid Nanoparticles: A Highly Versatile and Modular Tool for Membrane Protein Research

Saposin-derived lipid nanoparticles (SapNPs) are a new alternative tool for membrane protein reconstitution. Here we demonstrate the potential and advantages of SapNPs. We show that SapA has the lowest lipid specificity for SapNP formation. These nanoparticles are modular and offer a tunable range o...

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Detalles Bibliográficos
Autores principales: Flayhan, Ali, Mertens, Haydyn D.T., Ural-Blimke, Yonca, Martinez Molledo, Maria, Svergun, Dmitri I., Löw, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5807053/
https://www.ncbi.nlm.nih.gov/pubmed/29413323
http://dx.doi.org/10.1016/j.str.2018.01.007