Cargando…

Structure of the Deactive State of Mammalian Respiratory Complex I

Complex I (NADH:ubiquinone oxidoreductase) is central to energy metabolism in mammalian mitochondria. It couples NADH oxidation by ubiquinone to proton transport across the energy-conserving inner membrane, catalyzing respiration and driving ATP synthesis. In the absence of substrates, active comple...

Descripción completa

Detalles Bibliográficos
Autores principales: Blaza, James N., Vinothkumar, Kutti R., Hirst, Judy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5807054/
https://www.ncbi.nlm.nih.gov/pubmed/29395787
http://dx.doi.org/10.1016/j.str.2017.12.014